Studies Directed toward the Synthesis of Nakadomarin A.
نویسندگان
چکیده
The application of a Pummerer-initiated tandem reaction cascade leads to the highly stereoselective formation of the tetracyclic core of Nakadomarin A.
منابع مشابه
Synthetic Studies Towards the Core Structure of Nakadomarin A by a Thioamide-Based Strategy
The tricyclic BCD substructure of the marine natural product nakadomarin A has been synthesised. The strategy utilised a key carbon-carbon bond-forming reaction between a furan and an N-acyliminium ion derived from a secondary thiolactam. In addition, a novel three-component coupling reaction between a thioamide, an allylic bromide and an isocyanate, leading to the establishment of two new ster...
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ورودعنوان ژورنال:
- Tetrahedron letters
دوره 52 17 شماره
صفحات -
تاریخ انتشار 2011